Systems and methods for enhanced SCODA
US8518228B2 · kind B2 · utility
14Cited by
39References
34Claims
0Family size
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Key dates
| Filing date | Jun 3, 2011 |
| Grant date | Aug 27, 2013 |
| Priority date | — |
| Expiry date | Jul 31, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/385
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods and apparatus for separating, concentrating and/or detecting molecules based on differences in binding affinity to a probe are provided. The molecules may be differentially modified. The molecules may be differentially methylated nucleic acids. The methods can be used in fields such as epigenetics or oncology to selectively concentrate or detect the presence of specific biomolecules or differentially modified biomolecules, to provide diagnostics for disorders such as fetal genetic disorders, to detect biomarkers in cancer, organ failure, disease states, infection or the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.