Patent · US Active

Serine protease derivatives and uses in the prevention or the treatment of blood coagulation disorders

US8518400B2 · kind B2 · utility

1Cited by

0References

10Claims

0Family size

Assignee

Institut National de la Sante et de la Recherche Medicale (INSERM) · FR

Inventors

Olivier Christophe · Le Kremlin-Bicêtre, FR
Cecile Denis · Le Kremlin-Bicêtre, FR
Ghislaine Cherel · Le Kremlin-Bicêtre, FR
Paul Gueguen · Brest, FR

Key dates

Filing date	Jan 2, 2013
Grant date	Aug 27, 2013
Priority date	—
Expiry date	Jan 2, 2033

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Y304/21069
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The present invention relates to chimeric derivatives of serine protease zymogen containing the activation peptide of factor X or a fragment thereof for improving the half-life of said derivatives. Preferably, said chimeric derivatives are protein C and factor X derivatives. The invention also relates to said derivatives for the prevention or treatment of blood coagulation disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.