Patent · US Active

Salts of (R)-7-[3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-trifluoromethyl-5,6,7,8-tetrahydroimidazo[1,5-a] pyrazine-1-carboxylic acid, preparation method and medical use thereof

US8518946B2 · kind B2 · utility

1Cited by

1References

5Claims

0Family size

Assignees

Inventors

Peng Cho Tang · Moraga, US
Piaoyang Sun · Lianyungang, CN
Fanglong Yang · Shanghai, CN
Jindong LIANG · Shanghai, CN
Guangyuan Shen · Shanghai, CN
Yang Wang · Kingston, CA
Jiang Fan · Hubei, CN

Key dates

Filing date	Sep 2, 2011
Grant date	Aug 27, 2013
Priority date	—
Expiry date	Sep 2, 2031

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Pharmaceutically acceptable salts of (R)-7-[3-amino-4-(2,4,5-trifluorophenyl)-butyryl]-3-trifluoromethyl-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-formic acid, their preparation methods, compositions containing the said pharmaceutical salts and their use as medicaments, especially as dipeptidyl peptidase IV (DPP-IV) inhibitors are disclosed. Of the many acceptable salts, one example is the following.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.