Cyclohexyl-azetidinyl antagonists of CCR2
US8518969B2 · kind B2 · utility
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10Claims
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Key dates
| Filing date | Jun 16, 2011 |
| Grant date | Aug 27, 2013 |
| Priority date | — |
| Expiry date | Jun 16, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention comprises compounds of Formula I.wherein: R1, R2, R4, J, Q, and A are as defined in the specification. The invention also comprises a method of preventing, treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is type II diabetes, obesity and asthma. The invention also comprises a method of inhibiting CCR2 activity in a mammal by administration of a therapeutically effective amount of at least one compound of Formula I.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.