Monoclonal human tumor-specific antibody

US8519106B2 · kind B2 · utility

Assignee

• Universitat Zurich · CH

Inventors

• Christoph Esslinger · Bellinzona, CH
• Sandra Künzle · Bellinzona, CH
• Irene Abela · Ennetbaden, CH
• Alfred Zippelius · Munich, DE
• Dirk Jager · New York, US
• Alexander Knuth · Frankfurt am Main, DE
• Roger Nitsch · Zumikon, CH
• Holger Moch · Bellinzona, CH
• Norbert Göbels · Suhr, CH

Key dates

• Filing date: Mar 13, 2008
• Grant date: Aug 27, 2013
• Expiry date: Dec 24, 2028

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2317/21
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are novel human tumor-specific antibodies as well as fragments, derivatives and variants thereof that recognize tumor-associated antigen NY-ESO-1. In addition, pharmaceutical compositions comprising such antibodies and mimics thereof in the treatment of tumors are described.