Preparation of 6-alpha-amino N-substituted morphinans by catalytic hydrogen transfer
US8519133B2 · kind B2 · utility
4Cited by
24References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 10, 2010 |
| Grant date | Aug 27, 2013 |
| Priority date | — |
| Expiry date | Apr 8, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P25/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides processes for the stereoselective synthesis of 6-alpha-amino N-substituted morphinans. In particular, the invention provides processes for the reductive amination of 6-keto N-substituted morphinans by catalytic hydrogen transfer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.