Controlled drug delivery using a zein layer modified with levulinic acid
US8523937B2 · kind B2 · utility
3Cited by
10References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 19, 2008 |
| Grant date | Sep 3, 2013 |
| Priority date | — |
| Expiry date | Mar 12, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2420/08
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
The disclosure relates to medical devices coated with zein admixed with levulinic acid. The medical device may further include a therapeutic agent in contact with zein admixed with levulinic acid. Zein admixed with levulinic acid allows the therapeutic agent to be retained on the device during delivery and also controls the elution rate of the therapeutic agent following implantation. The disclosure further relates to methods of delivering a therapeutic agent on said medical devices as well as their use especially in the form of stents for prevention of restenosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.