Process for obtaining 17-spirolactones in steroids

US8524693B2 · kind B2 · utility

Assignee

• CRYSTAL PHARMA, S.A.U. · ES

Inventors

• Jesús Miguel Iglesias Retuerto · Laguna de Duero, ES
• Luis Gerardo Gutiérrez Fuentes · Laguna de Duero, ES
• Antonio Lorente Bonde-Larsen · Laguna de Duero, ES

Key dates

• Filing date: Jun 16, 2010
• Grant date: Sep 3, 2013
• Expiry date: Jun 3, 2031

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J53/008
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to processes for obtaining steroids with a spirolactone group in position 17, particularly to industrially obtaining 6β,7β; 15β,16β-dimethylene-3-oxo-17α-pregn-4-ene-21,17-carbolactone, commonly known as Drospirenone, as well as to intermediates useful in said process.