Tetrahydroisoquinoline sulfonamide derivatives, the preparation thereof, and the use of the same in therapeutics
US8524700B2 · kind B2 · utility
1Cited by
4References
12Claims
0Family size
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Key dates
| Filing date | Aug 24, 2012 |
| Grant date | Sep 3, 2013 |
| Priority date | — |
| Expiry date | Aug 24, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The disclosure relates to tetrahydroisoquinoline sulfonamide compounds of formula I:wherein R1, R2, n and B are as defined in the disclosure, their preparation and their use in therapies for the treatment of central nervous system diseases such as vigilance and sleep disorders, narcolepsy, Alzheimer's disease and other dementias, Parkinson's disease, attention disorders in hyperkinetic children, memory and learning disorders, epilepsy, schizophrenia, moderate cognitive disorders, depression, anxiety, sexual dysfunction, dizziness and travel sickness.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.