Patent · US Active

Substituted benzoazepines as toll-like receptor modulators

US8524702B2 · kind B2 · utility

5Cited by

2References

20Claims

0Family size

Assignees

VentiRx Pharmaceuticals, Inc. · US
Array BioPharma, Inc. · US

Inventors

James Jeffry Howbert · Bellevue, US
Gregory Dietsch · Snohomish, US
Robert Hershberg · Seattle, US
Laurence E. Burgess · Boulder, US
George A. Doherty · Libertyville, US
C. Todd Eary · Longmont, US
Robert D. Groneberg · Boulder, US
Zachary Jones · Boulder, US

Key dates

Filing date	Aug 18, 2010
Grant date	Sep 3, 2013
Priority date	—
Expiry date	Mar 26, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D403/14
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.