Patent · US Active

7-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(ADP-ribose) polymerase inhibitors

US8524714B2 · kind B2 · utility

0Cited by

18References

1Claims

0Family size

Assignee

Janssen Pharmaceuticals, Inc. · BE

Inventors

Dominique Jean-Pierre Mabire · La Saussaye, FR
Jérôme Emile Georges Guillemont · Andé, FR
Jacobus Alphonsus Josephus Van Dun · Kasterlee, BE
Maria Victorina Francisca Somers · Vosselaar, BE
Walter Boudewijn Leopold Wouters · Kapellen, BE

Key dates

Filing date	Mar 14, 2011
Grant date	Sep 3, 2013
Priority date	—
Expiry date	Mar 14, 2031

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D401/06
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides compounds of formula (I), their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I)wherein n, R1, R2, R3, R4, R5, R6 and X have defined meanings.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.