Patent · US Active

Macrocyclic indoles as hepatitis C virus inhibitors

US8524716B2 · kind B2 · utility

24Cited by
4References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 23, 2008
Grant dateSep 3, 2013
Priority date
Expiry dateFeb 2, 2030

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D513/08
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to inhibitors of HCV replication of formula (I), the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and the stereochemically isomeric forms thereof,wherein R1; R3; and R4 have the meaning defined in the claims.The present invention also relates to processes for preparing said compounds, pharmaceutical compositions containing them and their use in HCV therapy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.