Patent · US Active

Methods of using diaminopyrimidine as P2X3 and P2X⅔ receptor modulators for treatment of respiratory and gastrointestinal diseases

US8524725B2 · kind B2 · utility

1Cited by
2References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 19, 2011
Grant dateSep 3, 2013
Priority date
Expiry dateJul 19, 2031

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P43/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I):or a pharmaceutically acceptable salt thereof,wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.