Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8524731B2 · kind B2 · utility
1Cited by
125References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 17, 2006 |
| Grant date | Sep 3, 2013 |
| Priority date | — |
| Expiry date | Apr 24, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.