Patent · US Active

Bi- and polycyclic substituted isoquinoline and isoquinolinone derivatives

US8524737B2 · kind B2 · utility

0Cited by

4References

37Claims

0Family size

Assignee

Sanofi · FR

Inventors

Oliver Plettenburg · Kelkheim, DE
Katrin Lorenz · Frankfurt am Main, DE
Matthias Loehn · Frankfurt am Main, DE
Olivier Duclos · Paris, FR
Sandrine Biscarrat · Paris, FR

Key dates

Filing date	Jun 18, 2009
Grant date	Sep 3, 2013
Priority date	—
Expiry date	Oct 18, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D495/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to bi- and polycyclic substituted isoquinoline and isoquinolinones of the formula (I) wherein R1 to R12 are as defined in the application useful for the treatment and/or prevention of diseases associated with Rho-kinase and/or Rho-kinase mediated phosphorylation of myosin light chain phosphatase, and compositions containing such compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.