Tetraazaporphyrin-based compounds and their uses

US8524891B2 · kind B2 · utility

Assignee

• BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE · US

Inventors

• Robert P. Hammer · Baton Rouge, US
• Steven A. Soper · Baton Rouge, US
• Serhii Pakhomov · Baton Rouge, US
• Timothy J. Jensen · Mebane, US
• Michael W. Allen · Fitchburg, US
• Irina V. Nesterova · Baton Rouge, US
• Maria da Graça Henriques Vicente · Baton Rouge, US

Key dates

• Filing date: Jul 14, 2006
• Grant date: Sep 3, 2013
• Expiry date: Mar 22, 2030

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P35/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Asymmetrically substituted metal-phthalocyanine compounds are disclosed. These compounds and other phthalocyanine-derivatives are used in bioimaging, bioanalysis, FRET and quenching techniques, photodynamic therapy, DNA analysis for cells, proteins, tissues and other biological entities, and other applications. Near-infrared fluorescence minimizes matrix effects typically seen in other methods of analyzing biochemical entities in cells, proteins, tissues and other biological entities.