Method for polymerizing a small oligonucleotide, and use of a high-molecular oligonucleotide prepared by the polymerization method
US8530047B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Mar 2, 2010 |
| Grant date | Sep 10, 2013 |
| Priority date | — |
| Expiry date | Mar 2, 2030 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/2998
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The oligonucleotide polymerization method of the present invention is advantageous in that an oligonucleotide with a small molecular weight can be easily polymerized into high-molecular weight oligonucleotides. Further, the high-molecular oligonucleotide prepared by the method of the present invention can bind to hydrophilic high-molecular materials or inorganic materials, and then can be stably delivered to a living body. Therefore, the high-molecular oligonucleotide prepared by the method of the present invention can be widely used for treating various diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.