Detection of risk of pre-eclampsia
US8530150B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 24, 2010 |
| Grant date | Sep 10, 2013 |
| Priority date | — |
| Expiry date | Sep 27, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/368
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of detecting a risk of a pregnant female mammal developing pre-eclampsia or a complication linked thereto, or of a fetus of the pregnant female mammal developing a fetal or neonatal deficiency linked to maternal pre-eclampsia, comprises detecting the level of a VEGFxxxb in a sample from the pregnant female mammal at less than about 24 weeks of gestation and comparing the detected level with a reference level. A reduced level in the sample from the pregnant female mammal is indicative of a risk of the pregnant female mammal developing pre-eclampsia or a complication linked thereto or of the fetus developing the fetal or neonatal deficiency linked to maternal pre-eclampsia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.