Dyes and labeled molecules
US8530195B2 · kind B2 · utility
2Cited by
34References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 22, 2010 |
| Grant date | Sep 10, 2013 |
| Priority date | — |
| Expiry date | Jun 22, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/686
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Dimeric and trimeric nucleic acid dyes, and associated systems and methods are provided. Such a dye may form a hairpin-like structure that enables it to stain nucleic acids via a release-on-demand mechanism, for example. Such a dye may have low background fluorescence in the absence of nucleic acids and high fluorescence in the presence of nucleic acids, upon binding therewith, for example. A dye provided herein may be useful in a variety of applications, such as in DNA quantitation in real-time PCR, for example.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.