Patent · US Active

Y-shaped polyethylene glycol modified G-CSF, the preparation and use thereof

US8530417B2 · kind B2 · utility

1Cited by

1References

12Claims

0Family size

Assignee

Biosteed Gene Expression Tech. Co., Ltd. · CN

Inventors

Shiyuan Wang · Fujian, CN
Jianhua Zheng · Lo Wu, CN
Li Jing Sun · Hexi District, CN
Huili Cai · Fujian, CN
Meihua Yang · Hillsborough Township, US
Yan He · Hayward, US
Ping Chen · Fujian, CN
Hongyuan Deng · Fujian, CN
Liping Zhong · Riverview Drive, CN
Shuying Huang · Fujian, CN

Key dates

Filing date	Dec 29, 2007
Grant date	Sep 10, 2013
Priority date	—
Expiry date	Mar 18, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K14/535
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to granulocyte colony stimulating factor (G-CSF) modified with Y-shaped branched polyethylene glycol (YPEG-G-CSF) at a specific lysine (Lys 17) and the preparation thereof, as well as the pharmaceutical composition comprising YPEG-G-CSF and use thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.