Sterile hyaluronic acid solutions
US8530641B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Aug 1, 2012 |
| Grant date | Sep 10, 2013 |
| Priority date | — |
| Expiry date | Aug 1, 2032 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0072
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Sterilized aqueous solution comprising 0.04% to 0.8% by weight hyaluronic acid with a weight average molecular weight from 0.6 MDa to 3.6 MDa, and one or more buffer components selected from the group consisting of boric acid, sodium borate and sodium dihydrogen phosphate. The aqueous solution also has an ionic strength equivalent to an aqueous concentration of sodium chloride from 4% to 18% by weight of sodium chloride and a pH from 6.4 to 7.2. The solution is also filtered through a filter medium that has an average pore size of 0.25 μm or less to provide a sterilized high salt, hyaluronic acid solution.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.