Method of producing fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether
US8530704B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Aug 25, 2009 |
| Grant date | Sep 10, 2013 |
| Priority date | — |
| Expiry date | Apr 7, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C41/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a preparation method of fluoromethyl 1,1,1,3,3,3-hexafluoroisopropyl ether by reacting CH2FX with 1,1,1,3,3,3-hexafluoroisopropanol in the presence of acid-binding agent. The reaction can be also preformed in the presence of solvent and/or phase-transfer catalyst. The present method has the advantages of simple reaction, manageable control condition, high material conversion and product yield, and the product can be easily separated. The obtained fluoromethyl 1,1,1,3,3,3-hexafluoroisoprophyl ether can be used as a safe inhalation anesthetics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.