Diagnostic methods for osteoporosis
US8535238B2 · kind B2 · utility
1Cited by
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11Claims
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Key dates
| Filing date | Jun 20, 2005 |
| Grant date | Sep 17, 2013 |
| Priority date | — |
| Expiry date | Oct 15, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01J3/44
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods of diagnosing bone disease such as osteoporosis are provided. The methods comprise detecting changes in the physical or chemical structure of a keratinized tissue as correlates of disease. The methods include detecting changes in the hardness, modulus, or level of sulfur bonding, particularly the level of disulfide bonding, in a keratinized tissue sample such as nail, hair, or skin. Changes in these variables serve as diagnostic markers of bone diseases that are associated with changes in bone elasticity and bone density.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.