Methods and composition of extended delivery of water insoluble drugs
US8535716B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 1, 2005 |
| Grant date | Sep 17, 2013 |
| Priority date | — |
| Expiry date | Apr 7, 2033 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5057
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical composition is provided that includes an active ingredient in the form of a powder or granule, a water soluble high molecular weight excipient and a water insoluble hydrophilic amphiphilic excipient. These ingredients are solution mixed and dried to form a modified pharmaceutical ingredient in simultaneous contact with both the water soluble high molecular weight excipient and the water insoluble hydrophilic amphiphilic excipient. Adjuvants are compacted about the modified pharmaceutical ingredient as well as a release control agent. The release control agent being present at levels from 1 to 40 total weight percent of the pharmaceutical composition.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.