Biohybrid elastomeric scaffolds and methods of use thereof

US8535719B2 · kind B2 · utility

Assignee

• University of Pittsburgh—Of the Commonwealth System of Higher Education · US

Inventors

• Stephen F. Badylak · Lafayette, US
• Donald Freytes · Pittsburgh, US
• Thomas Gilbert · Leek Wootton, GB
• Jianjun Guan · Dublin, US
• John J. Stankus · Campbell, US
• William R. Wagner · Escondido, US

Key dates

• Filing date: Jul 6, 2007
• Grant date: Sep 17, 2013
• Expiry date: Nov 28, 2031

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Provided herein is a biohybrid elastomeric scaffold comprising a synthetic polymeric component and a biological polymeric component. The scaffold can be fabricated to have many different forms, non-limiting examples of which include a non-woven fibrous mesh or in a porous composite. Methods of use of the biohybrid elastomeric scaffolds in wound healing and tissue regeneration are also provided.