Synthetic peptide amides and dimers thereof
US8536131B2 · kind B2 · utility
49Cited by
7References
23Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 27, 2010 |
| Grant date | Sep 17, 2013 |
| Priority date | — |
| Expiry date | Jan 21, 2031 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to synthetic peptide amide ligands of the kappa opioid receptor and particularly to agonists of the kappa opioid receptor that exhibit low P450 CYP inhibition and low penetration into the brain. The synthetic peptide amides of the invention conform to the structure:The compounds are useful in the prophylaxis and treatment of pain and inflammation associated with a variety of diseases and conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.