Patent · US Active

Benzyl and pyridinyl derivatives as modulators of the hedgehog signaling pathway

US8536168B2 · kind B2 · utility

29Cited by

7References

5Claims

0Family size

Assignee

Novartis AG · CH

Inventors

Miao Dai · Shanghai, CN
Feng He · Nanhu, CN
Rishi Jain · Cambridge, US
Rajesh Karki · Quincy, US
Joseph Kelleher · Cambridge, US
John Lei · Cambridge, US
Luis Llamas · Madrid, ES
Michael A. Mcewan · Cambridge, US
Karen Miller-Moslin · Princeton, US
Lawrence Bias Perez · Cambridge, US
Stefan Peukert · Frankfurt am Main, DE
Naeem Yusuff · Cambridge, US

Key dates

Filing date	Mar 13, 2008
Grant date	Sep 17, 2013
Priority date	—
Expiry date	Apr 11, 2030

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07F9/65583
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present disclosure relates to compounds relating to the diagnosis and treatment of pathologies relating to the Hedgehog pathway, including but not limited to tumor formation, cancer, neoplasia, and non-malignant hyperproliferative disorders; specifically relating to compounds of formula I:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.