Patent · US Active

Anticalins

US8536307B2 · kind B2 · utility

10Cited by

3References

11Claims

0Family size

Assignee

Pieris AG · DE

Inventors

Arne Skerra · Freising, DE
Gerald Beste · Munich, DE
Frank Schmidt · Zorneding, DE
Thomas Stibora · Michendorf, DE

Key dates

Filing date	Mar 19, 2012
Grant date	Sep 17, 2013
Priority date	—
Expiry date	Mar 19, 2032

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2799/021
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

The invention relates to the production of novel proteins exhibiting binding activity for certain ligands, the so-called anticalins. To this end, the structure of peptides of the lipocalin family is modified by amino acid replacement in their natural ligand binding pocket using genetic engineering methods. Like immunoglobulin, the anticalin thus obtained can be used to identify or bind molecular structures.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.