Steroidal ligands and their use in gene switch modulation
US8536354B2 · kind B2 · utility
1Cited by
2References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 16, 2009 |
| Grant date | Sep 17, 2013 |
| Priority date | — |
| Expiry date | May 26, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/002
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to steroidal ligands for use in nuclear receptor-based inducible gene expression systems. The invention further relates to methods of modulating the expression of genes of interest with a system containing one or more nuclear receptor complexes and one or more steroidal ligands. Further aspects include ligand compositions including therapeutic compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.