Desorption and ionization method and device
US8536523B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 12, 2010 |
| Grant date | Sep 17, 2013 |
| Priority date | — |
| Expiry date | Nov 19, 2030 |
Classification
- Technology area (CPC H)Electricity
- CPC primaryH01J49/049
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention involves a method and a device for sequentially desorbing and ionizing mixed analytes on a solid surface with a gradual temperature scan, and continuously collecting data for multiple times in the gradual desorption and ionization process. By gradually increase the temperature of at least one part of the sample, the analytes with different thermal desorption capabilities are sequentially desorbed from surfaces of the solid sample, thereby providing a sample pre-separation scheme, so as to reduce difficulties to subsequent mass spectrum detection. Meanwhile, since mass spectrum data of the analytes with different boiling points is collected for multiple times during a temperature scan, the analytes with a low boiling point can be detected first at lower temperature in order to avoid rapid exhaustion at higher temperature, thereby improving the detection efficiency of the analytes with low boiling points.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.