Patent · US Active

Complement receptor 1 and 2 fusion proteins

US8540997B2 · kind B2 · utility

0Cited by
19References
13Claims
0Family size

Assignees

Inventors

Key dates

Filing dateJun 16, 2011
Grant dateSep 24, 2013
Priority date
Expiry dateJun 16, 2031

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Modulation of the complement system represents a therapeutic modality for numerous pathologic conditions associated with complement activation. In a strategy to prepare complement inhibitors that are targeted to sites of complement activation and disease, compositions comprising a complement inhibitor linked to complement receptor (CR) 2 are disclosed. The disclosed are compositions can be used in methods of treating pathogenic diseases and inflammatory conditions by modulating the complement system.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.