L-proline cis-4-hydroxylase and use thereof to produce cis-4-hydroxy-L-proline
US8541209B2 · kind B2 · utility
6Cited by
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4Claims
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Key dates
| Filing date | May 12, 2009 |
| Grant date | Sep 24, 2013 |
| Priority date | — |
| Expiry date | Jan 13, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y114/11002
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Development of a method of economically and efficiently producing cis-4-hydroxy-L-proline. The present invention provides L-proline cis-4-hydroxylase. This enzyme may be derived from Lotus corniculatus rhizobia, Mesorhizobium loti or Medicago sativa rhizobia, Sinorhizobium meliloti. The present invention provides a method of producing cis-4-hydroxy-L-proline from L-proline by using this enzyme. The present invention provides a recombinant vector containing a polynucleotide encoding the enzyme and a transformant containing the vector.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.