Patent · US Active

Thiadiazole derivatives for the treatment of neurodegenerative diseases

US8541406B2 · kind B2 · utility

0Cited by

2References

28Claims

0Family size

Assignee

ReMYND N.V. · BE

Inventors

Gerard Griffioen · Linden, BE
Kristel Marie Edith Coupet · Dilbeek, BE
Hein Roger Duhamel · Kessel-Lo, BE
Stefaan Wera · Bierbeek, BE
Ellen Gommé · Opvelp, BE
Nele Van Damme · Kessel-Lo, BE
Ingrid Van Der Auwera · Langdorp, BE
Marleen Lox · Tienen, BE
Tom Van Dooren · Koningshooikt, BE
Tine Decruy · Damme, BE

Key dates

Filing date	Aug 6, 2008
Grant date	Sep 24, 2013
Priority date	—
Expiry date	Jul 25, 2032

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P25/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention provides specifically substituted 1,2,4-thiadiazole derivatives for use in the treatment of an α-synucleopathy such as Parkinson's disease, diffuse Lewy body disease, traumatic brain injury, amyotrophic lateral sclerosis, Niemann-Pick disease, Hallervorden-Spatz syndrome, Down syndrome, neuroaxonal dystrophy, multiple system atrophy and Alzheimer's disease. This invention also provides various methods for producing such substituted 1,2,4-thiadiazole derivatives.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.