Stabilized melanocortin ligands
US8541545B2 · kind B2 · utility
4Cited by
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11Claims
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Key dates
| Filing date | Aug 30, 2010 |
| Grant date | Sep 24, 2013 |
| Priority date | — |
| Expiry date | Aug 30, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compositions and methods are disclosed for a non-naturally occurring melanocortin ligand comprised of a melanocortin analog coupled to a degradation-resistant C-terminal extension and, optionally, an N-terminal extension, to produce a stable melanocortin ligand having diminished or abolished cardiovascular activity while retaining desired melanocortin regulatory activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.