Compounds and methods for reversible modification of biologically active molecules
US8541548B2 · kind B2 · utility
40Cited by
20References
10Claims
0Family size
Assignee
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Key dates
| Filing date | Jun 17, 2008 |
| Grant date | Sep 24, 2013 |
| Priority date | — |
| Expiry date | Apr 4, 2030 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0362
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed compounds for reversibly modification of biologically active molecules. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery conjugates. The use of reversible modification provides for physiologically responsive activity modulation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.