Lipid conjugated cyclic carbonate derivatives, their synthesis, and uses
US8541605B2 · kind B2 · utility
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16Claims
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Key dates
| Filing date | May 11, 2008 |
| Grant date | Sep 24, 2013 |
| Priority date | — |
| Expiry date | Aug 19, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides processes for the preparation of lipid conjugated cyclic carbonate derivatives. More specifically, the present disclosure is based on the finding that reacting lipids, such as, ceramides, with N,N′-disuccinimidyl derivative, resulted in the formation of, isolatable, substituted cyclic [1,3]-dioxan-2-one and [1,3]-dioxan-2-thione compounds. These isolatable cyclic substituted compounds and derivatives thereof may be used for various applications, such as in vaccination.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.