Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation

US8541618B2 · kind B2 · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Derek Lowe · Scotch Plains, US
• Philip Wickens · Wallingford, US
• Xin Ma · Bethany, US
• Mingbao Zhang · Millwood, US
• William Bullock · Easton, US
• Philip Coish · New Haven, US
• Ingo Andreas Mugge · New Haven, US
• Andreas Stolle · Wuppertal, DE
• Ming Wang · Montgomery, US
• Yamin Wang · Hubei, CN
• Chengzhi Zhang · San Diego, US
• Hai-Jun Zhang · Boxborough, US
• Lei Zhu · Hefei, CN
• Manami Tsutsumi · Stratford, US
• James N. Livingston · Guilford, US

Key dates

• Filing date: Feb 25, 2011
• Grant date: Sep 24, 2013
• Expiry date: Feb 15, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2602/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.