Method for selectively crystallizing a Z isomer of iopromide
US8541620B2 · kind B2 · utility
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12Claims
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Key dates
| Filing date | Oct 21, 2009 |
| Grant date | Sep 24, 2013 |
| Priority date | — |
| Expiry date | Apr 4, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C231/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a method for selectively crystallizing Z isomer of iopromide of formula (I) comprising a) dissolving a crude iopromide comprising a mixture of E and Z isomers or a concentrate thereof in an alcohol, and b) heating the resulting alcohol solution to obtain crystalline of Z isomer of iopromide; and a method for preparing a composition comprising the crystalline Z isomer of iopromide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.