Anti-c-Met antibody
US8545839B2 · kind B2 · utility
10Cited by
13References
33Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 1, 2010 |
| Grant date | Oct 1, 2013 |
| Priority date | — |
| Expiry date | Jun 18, 2031 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/91205
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a novel antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor both in a ligand-dependent and in a ligand-independent manner, with an improved antagonistic activity, said antibody comprising a modified hinge region.The invention also relates to a composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.