Glp-1 analogue formulations
US8546326B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 6, 2006 |
| Grant date | Oct 1, 2013 |
| Priority date | — |
| Expiry date | Aug 4, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P3/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to compositions forming a low viscosity mixture of: a) at least one neutral diacyl lipid, such as a diacyl glycerol; b) at least one phospholipid, such as a phosphatidyl choline; c) at least one biotolerable solvent, such as an oxygen containing solvent; d) at least one GLP-1 analogue; wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The invention further relates to methods of treatment comprising administration of such compositions, especially in treating diabetes, and to pre-filled administration devices and kits containing the formulations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.