Patent · US Active

Glp-1 analogue formulations

US8546326B2 · kind B2 · utility

20Cited by
18References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 2006
Grant dateOct 1, 2013
Priority date
Expiry dateAug 4, 2029

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P3/10
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to compositions forming a low viscosity mixture of: a) at least one neutral diacyl lipid, such as a diacyl glycerol; b) at least one phospholipid, such as a phosphatidyl choline; c) at least one biotolerable solvent, such as an oxygen containing solvent; d) at least one GLP-1 analogue; wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The invention further relates to methods of treatment comprising administration of such compositions, especially in treating diabetes, and to pre-filled administration devices and kits containing the formulations.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.