Patent · US Active

Liquid formulation of G-CSF conjugate

US8546328B2 · kind B2 · utility

0Cited by

7References

30Claims

0Family size

Assignee

BIOGENERIX GMBH · DE

Inventors

Walter Hinderer · Rodgau, DE
Christian Scheckermann · Ehrenkirchen, DE

Key dates

Filing date	Aug 27, 2008
Grant date	Oct 1, 2013
Priority date	—
Expiry date	Sep 4, 2029

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention relates to a liquid pharmaceutical composition comprising a granulocyte colony stimulating factor polypeptide conjugated with a polymer, the composition having a pH value in the range of 4.5 to 5.5. The composition further comprises a surfactant and optionally one or more other pharmaceutically acceptable excipients. Further, the composition of the invention is free from tartaric acid or salts thereof and from succinic acid and salts thereof as buffering agents and does not contain amino acids as stabilizer. The composition has a good storage stability and is especially useful for the prophylaxis and treatment of disorders and medical indications where granulocyte colony stimulating factor preparations are considered as useful remedies.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.