Patent · US Active

Factor VIII polypeptide having factor VIII:C activity

US8546332B2 · kind B2 · utility

0Cited by

1References

8Claims

0Family size

Assignee

Stichting Sanquin Bloedvoorziening · NL

Inventors

Petrus Lenting · Blois, FR
Jan Aart Van Mourik · Badhoevedorp, NL
Koenraad Mertens · Leiden, NL
Hans Pannekoek · Aalsmeer, NL
Peter Turecek · Klosterneuburg, AT
Hans-Peter Schwarz · Wien, AT
Friedrich Scheiflinger · Wien, AT

Key dates

Filing date	Feb 19, 2009
Grant date	Oct 1, 2013
Priority date	—
Expiry date	Dec 7, 2030

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K38/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Factor VIII polypeptides having FVIII:C activity that contain modifications in the A3 and/or C1 and/or C2 domains of the sequence of the light chain of Factor VIII, characterized by the binding affinity to low density lipoprotein receptor protein, and methods for producing the same.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.