Aminodihydrothiazine derivatives
US8546380B2 · kind B2 · utility
0Cited by
25References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 23, 2011 |
| Grant date | Oct 1, 2013 |
| Priority date | — |
| Expiry date | Sep 23, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A composition having BACE 1 inhibitory activity containing a compound represented by the formula (I):wherein ring A is an optionally substituted heterocyclic group;E is lower alkylene;X is S;R1 is a hydrogen atom or lower alkyl;R2a, R2b, R3a, R3b, R4a and R4b is each independently a hydrogen atom, halogen, or hydroxy etc.;n and m are each independently an integer of 0 to 3;n+m is an integer of 0 to 3;R5 is a hydrogen atom or substituted lower alkyl;or its pharmaceutically acceptable salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.