5,6-disubstituted oxindole-derivatives and use thereof for treating vasopressin-dependent diseases

US8546401B2 · kind B2 · utility

Assignee

• Abb Vie Deutschland Gmbh & Co. KG · DE

Inventors

• Wilfried Braje · Ludwigshafen, DE
• Thorsten Oost · Biberach an der Riß, DE
• Astrid Netz · Mannheim, DE
• Wolfgang Wernet · Ludwigshafen, DE
• Liliane Unger · Ludwigshafen, DE
• Wilfried Hornberger · Wiesbaden, DE
• Wilfried Lubisch · Mannheim, DE

Key dates

• Filing date: Dec 5, 2008
• Grant date: Oct 1, 2013
• Expiry date: Dec 5, 2028

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel 5,6-disubstituted oxindole derivatives and pharmaceutically acceptable salts thereof, and pharmaceutical compositions comprising such derivatives, and to the use of such derivatives for the manufacture of a medicament, and methods of treating disorders in a subject in need thereof, such as vasopressin-dependent disorders, using 5,6-disubstituted oxindole derivatives.