Patent · US Active

Folate receptor binding conjugates of antifolates

US8546425B2 · kind B2 · utility

9Cited by

3References

11Claims

0Family size

Assignees

Purdue Research Foundation · US
Endocyte, Inc. · IN

Inventors

Christopher Paul Leamon · West Lafayette, US
Iontcho Radoslavov Vlahov · West Lafayette, US
Philip S. Low · West Lafayette, US

Key dates

Filing date	Sep 17, 2009
Grant date	Oct 1, 2013
Priority date	—
Expiry date	Sep 17, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D487/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Conjugates of antifolates, releasable linkers, and drugs, and pharmaceutical compositions containing them are described. The conjugates are useful for treating diseases arising from pathogenic cell populations. Methods for treating such diseases are also described.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.