5-lipoxygenase-activating protein (FLAP) inhibitors

US8546431B2 · kind B2 · utility

Assignee

• Panmira Pharmaceuticals, LLC · US

Inventors

• John Howard Hutchinson · Village of La Jolla, US
• Petpiboon Prasit · Rancho Santa Fe, US
• Mark Moran · Orinda, US
• Jillian F. Evans · Carlsbad, US
• Yiwei Li · Ambler, US
• Jeannie M. Arruda · San Diego, US

Key dates

• Filing date: Oct 30, 2012
• Grant date: Oct 1, 2013
• Expiry date: Oct 30, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A method for treating a human comprises administering a therapeutically effective amount of 3-[3-tert-butylsulfanyl-1-[4-(6-methoxy-pyridin-3-yl)-benzyl]-5-(pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid or a pharmaceutically acceptable salt or a pharmaceutically acceptable N-oxide thereof, to the human in need.