Tetrazolones as inhibitors of fatty acid synthase
US8546432B2 · kind B2 · utility
4Cited by
62References
35Claims
0Family size
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Key dates
| Filing date | May 5, 2011 |
| Grant date | Oct 1, 2013 |
| Priority date | — |
| Expiry date | Aug 16, 2031 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are tetrazolone FASN inhibitors of the formula (I):or a pharmaceutically acceptable form thereof; wherein the variables RA, RB and RC are defined herein.Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.