Polymorphic forms of 2-(5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid and uses thereof

US8546436B2 · kind B2 · utility

Assignee

• Ardea Biosciences, Inc · US

Inventors

• Laszlo R. Treiber · San Diego, US
• Gabriel Galvin · Manlius, US
• Irina Zamansky · Oceanside, US
• Jean-Luc Girardet · San Diego, US

Key dates

• Filing date: Dec 28, 2011
• Grant date: Oct 1, 2013
• Expiry date: Feb 24, 2032

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D249/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Crystalline polymorph forms of 2-(5-bromo-4-(4-cyclopropyl naphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetic acid are described. Pharmaceutical compositions and the uses of such compounds, compound forms, and compositions for the treatment of a variety of diseases and conditions are also presented.