Pipecolic linker and its use for chemistry on solid support
US8546533B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Aug 28, 2009 |
| Grant date | Oct 1, 2013 |
| Priority date | — |
| Expiry date | Jun 12, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a pipecolic linker and its use as a solid-phase linker in organic synthesis. Said pipecolic solid-phase linker may be used for coupling functional groups chosen between primary amines, secondary amines, aromatic amines, alcohols, phenols and thiols. In particular, said pipecolic solid-phase linker may be used for peptide or pseudopeptide synthesis, such as the reverse N to C peptide synthesis or the retro-inverso peptide synthesis, or for the synthesis of small organic molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.