Proteasome inhibitors and methods of using the same
US8546608B2 · kind B2 · utility
2Cited by
31References
3Claims
0Family size
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Key dates
| Filing date | Sep 30, 2011 |
| Grant date | Oct 1, 2013 |
| Priority date | — |
| Expiry date | Sep 30, 2031 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/025
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.